Abstract: This paper reviewed paleoclimate simulations of warm periods in the Late Quaternary, including the last interglacial (130~115 kaBP) and the megainterstadial of the last glacial (40~30 kaBP), introduced the boundary conditions of simulated experiment and essential analogue results, and discussed the mechanisms of the warm climate, in order to provide an understanding of warm climate dynamics and to recognize the further changes in the global climate.