Abstract: Based on the Holocene climate evolution curve constructed with the Greenland ice core GISP2 and the integrated climate curves at the latitude of 30°～90°N, as well as the climate evolutionary curves recently acquired from the Holocene cave stalagmites, loess and lake sediments, the Holocene climatic rhythm stages has been established by this paper for Eastern China, which consists of 11 warm periods (numbered W1-W11) and 10 cold periods (numbered C1-C10). Correspondingly, the analysis of Holocene climatic events, such as floods, transgressions, regressions, glaciers, freezing and other climate events in the eastern China is conducted. Evidence confirms that there is a millennium scale rhythmical climate evolution in China during the Holocene. The cooling periods numbered C2, C4 and C6 have showed the considerable cooling and may correspond to the cooling events in 10, 8.2 and 5.3 kaBP, respectively. The warming period numbered W5 is corresponding to the Megathermal around 7 kaBP. It indicates that the Holocene climate change in eastern China is obviously influenced by land-sea interactions.